The Breast Unit was established in 2007 as a consequence of an over-12-year-long multidisciplinary approach to breast cancer diagnosis and treatment. The team, composed by oncologists, radiologists, radiotherapists, pathologists, cytologists, general and plastic surgeons, nuclear physicians, psycologists and physiatrics, meets once a week for patient's evaluation and for the definition of diagnostic and therapeutic strategies and scientific update. The breast unit arranges all the diagnostic steps, including mammotome and open biopsies; it provides care for all stages of breast cancer including oncoplastic surgery, immediate and delayed plastic reconstruction, sentinel node biopsy, breast irradiation, preoperative and adjuvant systemic therapy, treatment of locally advanced and metastatic breast cancer, rehabilitative and psychological support. The unit offers also a multidisciplinary approach for risk assessment and genetic counselling. As a University Hospital we have residents in all specialties such as breast and plastic surgery, oncology and radiology. The unit organizes one/two annual meetings about breast issues and the Breast Cancer Awareness Month (BCAM).