The Breast Unit was established in 2016 at Ospedale Policlinico San Martino IRCCS, in order to give patients a multidisciplinary approach to breast cancer diagnosis and treatment. The multidisciplinary team (oncologists, surgeons , radiologists, radiation oncologists, pathologists, genetist and gynecologists) meets once a week to define diagnostic and therapeutic strategies of all breast cancer patients. On average, 800 patients are evaluated every year at our Istitute. We provide care of breast cancer at every setting, including conservative and demolitive surgery with reconstruction and oncoplastic surgery, partial and whole breast irradiation, pre-operative and adjuvant systemic therapy, treatment of locally advanced and metastatic breast cancer, psychological and rehabilitative support. Our Breast Unit is the regional HUB of breast cancer genetic evaluation and fertility preservation strategy.