The Breast Unit of Salamanca University Hospital is part of the surgical department and provides multidiscipliary integrated breast cancer care since 1995. A team of breast oncoplastic surgeons, radiologists, medical oncologists, radiotherapy oncologists, pathologists, nurses, nuclear specialists, pathologists, radiologist, reconstructive plastic surgeons, geneticists, breast nurses and a psycho-oncologist treats patients according to most up to date international guidelines and clinical paths. In our Breast Unit we assist all the cases coming from the programme of breast cancer screening. Last year, we have treated 230 patients with newly diagnosed breast cancer disease, along with surgery for benign breast disease, while our outpatient diagnostic section saw about 5500 patients. All patients are discussed in the multidisciplinary (MDM) meeting before treatment starts, and in the postoperative MDM after surgery. Breast-conserving surgery is our goal with the aid of oncoplastic tecnics and intraoperative ultrasound. In selected patients, when a mastectomy is necessary, we indicate skin-sparing or nipple-sparing mastectomy wiht immediate reconstruction.